Good news for the Bolts: Joey Bosa is active for the first time since Week 3.
Bosa has missed the past three games with a hip injury, an issue he went into detail about on Friday.
The Chargers will have to rely on their depth in Week 8 as Quentin Johnston and Derius Davis are inactive against the Saints.
Hayden Hurst will also not play after being listed as doubtful coming into the game.
Offensive lineman Jordan McFadden and defensive lineman Justin Eboigbe are also inactive, as is quarterback Easton Stick.
Here is who won't suit up against the Saints:
WR Quentin Johnston
QB Easton Stick (emergency third QB)
WR Derius Davis
OL Jordan McFadden
TE Hayden Hurst
DL Justin Eboigbe
Here are New Orleans' inactives:
QB Derek Carr
WR Marquez Valdes-Scantling
WR Cedrick Wilson Jr.
LB Jaylan Ford
OL Nick Saldiveri
TE Dallin Holker
DT Khristian Boyd